What adjuvant endocrine therapy would you recommend for patients who have undergone prior gastrectomy?
More generally, do absorption issues effect the efficacy of tamoxifen and/or aromatase inhibitors?
Answer from: Medical Oncologist at Academic Institution
This is challenging with no good evidence based recommendations to my knowledge. In the past, with a patient post gastrectomy, I have elected to do tamoxifen therapy and checked absorption level by checking endoxifen level after a few weeks on therapy.