What adjuvant therapy do you recommend for early stage poorly differentiated small cell neuroendocrine carcinoma of the cervix after surgical resection?  

As Dr. @Tracilyn R. Hall has so eloquently explained, this is a rare and aggressive tumor. Often, what we think is early stage is not early stage at all. I would recommend CT or MRI brain imaging as well as a PET/CT. if there are no distant metastases, then I would offer at least 4, and up to 6 cycl...

Yes! With neuroendocrine small cell carcinoma, we know patients are at high risk for recurrence, particularly distant metastasis, with most studies reporting long term survival only when surgery is used in combination with adjuvant therapy. In the retrospective analysis performed by Pei et al., PMID...