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Radiation Oncology • Non-malignant Disease
What dose and fractionation do you use for gynecomastia prophylaxis?
SPCG-07 (Widmark et al) and a large Norwegian registry study (Aksnessæther BY IJROBP 2018) use 12-15Gy/1fx with electrons, but others use 3-5 fractions. Are electrons or photons preferable?
Answer from: Radiation Oncologist at Community Practice
As I answered on a previous thread to a question that was similarly posed, philosophically I would prefer electrons (less integral dose/more focused - IMHO) as opposed to photons. In terms of dose, it seem these days less is better with single fraction especially. Hence, the NICE (European)&nbs...
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Answer from: Radiation Oncologist at Community Practice
I treated a patient a few years ago who developed gynecomastia and mammodynia while take both leuprolide and enzalutamide.
I went with 20 Gy in 5 fractions using an en face electron setup. There was moderate reduction of the gynecomastia (it was not prominent to begin with) and complete reso...