What dose constraints do you use when treating gastric MALT or DLBCL with radiation therapy?
Answer from: Radiation Oncologist at Academic Institution
Treatment of the entire stomach is recommended for gastric MALT lymphoma. A dose of 24-30 Gy is recommended, generally in 1.5 Gy fractions to limit acute toxicity. I am starting to utilize 24 Gy more frequently though, most studies have used 30 Gy. Gastric MALT tends to be multifocal, is not well vi...
Comments
Radiation Oncologist at Ohio State University James Cancer Center Dr. @Christopher R. Kelsey - any opinion on offeri...
Radiation Oncologist at Duke University Medical Center For asplenic adults (and presumably this would inc...
Answer from: Radiation Oncologist at Academic Institution
Agree with Dr. @Kelsey's answer but would add the following comments:
Lymphomas are one of the few malignancies for which randomized dose/response data are available. For indolent histologies, including gastric malt, 24 Gy is equivalent to larger doses, and superior to 4 Gy. There is no establish...
Dr. @Christopher R. Kelsey - any opinion on offeri...
For asplenic adults (and presumably this would inc...