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Radiation Oncology • Melanoma/Skin Cancer
What dose-fractionation would you utilize for an unresectable localized cutaneous melanoma that has progressed on immunotherapy?
Specifically, for a melanoma of the axilla with proximity to the brachial plexus, how would you approach such a case to minimize chance of radiation-induced brachial plexopathy?
Answer from: Radiation Oncologist at Academic Institution
If the concern is to minimize the chance of radiation-induced brachial plexopathy, then it is advisable to keep the equivalent total dose below the tolerance of the brachial plexus. The preceding immunotherapy is not known to change the risk of radiation-induced brachial plexopathy. Contrary to popu...
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