What is the appropriate time interval to assess treatment response in primary vaginal SCC?

Would you delay salvage surgery for a stage I primary vaginal cancer with partial response but no new disease at 3 months after radiation (EBRT + brachytherapy boost) alone?

If this approach is accepted in HPV-mediated H&N and anal cancer, does the same principle apply for gynecologic SCC?

Answer from: Radiation Oncologist at Community Practice

I would favor biopsy before any intervention. If positive, would need surgical salvage (similar principle as cervical cancer).Beaty et al., PMID 34455989 This review gives some biological differences between cervical and other HPV-associated malignancies.

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Radiation Oncologist at Harold C Simmons Comprehensive Cancer Center/UT Southwestern
I agree with delaying surgical salvage for non-pro...

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What is the appropriate time interval to assess treatment response in primary vaginal SCC?

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