What is the best management for recurrent basal cell carcinoma after prior radiation and vismodegib?
Would re-irradiation be an appropriate option? What dose/field would you incorporate? If treating with standard fractionation, would you take the entire "bed" to 60Gy, 64-66Gy, or something else?
Answer from: Radiation Oncologist at Academic Institution
Recurrent basal cell carcinoma can be challenging to manage. It is important recognize that vismodegib is FDA approved for basal cell carcinoma that is not treatable with surgery or radiation therapy. In this case, if you think radiotherapy could be given again, vismodegib should have never been u...