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Radiation Oncology • Thoracic Malignancies
What is the optimal sequencing of systemic therapy and consolidative thoracic RT for oligometastatic NSCLC?
Do you favor systemic therapy for X cycles followed by restaging and then consolidative radiation (SBRT or CRT)? Or do you prefer up front thoracic directed therapy?
Answer from: Radiation Oncologist at Academic Institution
I personally prefer doing sequential therapy first, for 3-4 months, then reassess for continuing oligometastatic state. This is how it was done in the Gomez randomized phase II study in which a PFS and OS benefit was observed. I think that by doing systemic therapy first some patients who are rapidl...
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