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What is the role of neo-adjuvant chemotherapy in triple positive cT1c N0 breast cancer especially after recent data from KATHERINE trial?
Clinical T1c patients were included in the KATHERINE trial that often are treated with adjuvant paclitaxel and trastuzumab
Answer from: Medical Oncologist at Academic Institution
This is an interesting issue, and one discussed by Dan Hayes in his NEJM editorial accompanying the KATHERINE publication.T1cN0 triple positive disease in the original trial of adjuvant paclitaxel/traztuzumab x 12 weeks (Tolaney, NEJM 2016) had a 4 year EFS in excess of 97%. Therefore I am not sure ...
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