What is the role of SRS in the treatment of malignant gliomas?

When, if ever, would you consider up-front SRS for first line therapy?

Answer from: Radiation Oncologist at Community Practice

This is a good question that has been formally studied. RTOG 93-05 was a negative phase III randomized trial of chemo-RT with or without an up-front SRS boost for glioblastoma. Results were published in the Souhami et al., PMID 15465203. Tumors had to be 4 cm or smaller to be eligible. Tumors were a...

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Radiation Oncologist at Loma Linda University
Thank you for reminding us about the negative resu...

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What is the role of SRS in the treatment of malignant gliomas?

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