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Radiation Oncology • Thoracic Malignancies
What is the role of surgery in patients with Stage III NSCLC and N2 positive lymph nodes?
Should surgery followed by adjuvant chemotherapy and radiation be considered for non-bulky single station N2 disease?
Answer from: Radiation Oncologist at Community Practice
Interestingly:
Patients that were to get lobectomy has survival of 2.8 years with surgery and 1.8 years with CRT
However, for pneumonectomy patients, patients treated with surgery had survival of 1.6 years while those treated with CRT had a survival of 2.4 years.
So.. patients with disease ...
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Answer from: Radiation Oncologist at Community Practice
We conceived and published a trial that published on this precise question. (Albain Lancel Oncology (2009) 374: 379-386). The simple answer is that there is no proven role for surgery in stage IIIa (or IIIb). The study used SWOG data and platforms; 45 Gy + Plat Etop pre-op or to "full do...
Answer from: Radiation Oncologist at Community Practice
As the "cover story" of the exploratory analysis ran, there was an attempt to match factors of T, N and M; not specifically size, V-20, FEV1, or other clinically meanngfu; matter. Matched pair needs comparable matches to run more than one pass...there was very superficial "matches" in CRT subg...