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Topics:
Hematologic Malignancies • Medical Oncology • Myelodysplastic Syndromes • Leukemia • Internal Medicine • Hematology
What is your approach to CMML-MDS in an older patient with low risk disease who is becoming transfusion dependent?
Would you use a trial of dexamethasone for a patient with thrombocytopenia?
Answer from: Medical Oncologist at Academic Institution
The short answer is that we treat lower risk CMML much like we treat lower risk MDS, even though we don't have dedicated studies in CMML to support this approach. After addressing any reversible causes of anemia (iron or vitamin deficiencies, hemolysis, etc...), NCCN guidelines for MDS would recomme...
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