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Topics:
Internal Medicine • Rheumatology • Antiphospholipid Syndrome • Systemic lupus erythematosus • Cardiology • SLE • Endocarditis
What is your approach to diagnosis and evaluation of nonbacterial thrombotic endocarditis (Libman-Sacks)?
Patient with negative blood cultures, completed 6 weeks of IV antibiotics and vegetation persists. CT imaging without evidence of malignancy. No evidence SLE or APS.
Answer from: at Academic Institution
Nonbacterial thrombotic endocarditis (NBTE), also known as Libman-Sacks endocarditis, is a form of endocarditis characterized by the presence of sterile vegetations on cardiac valves. It is most commonly associated with systemic autoimmune conditions, notably systemic lupus erythematosus (SLE) and a...
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Answer from: at Academic Institution
Noninfectious endocarditis is best divided into inflammatory vegetation best illustrated by Libman Sacks lesions vs, in the alternative, a primary thrombotic vegetation also known both as marantic and, less commonly in literature, as murantic endocarditis and associates with hypercoagulable states s...
Answer from: at Community Practice
What is the microscopic composition of the vegetations? If Non-thrombotic, Non-infectious, seems no role for anticoagulation.