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Nephrology • Transplant nephrology
What is your approach to dose adjusting mycophenolate in a kidney transplant recipient who is transitioned from tacrolimus to cyclosporine?
Answer from: at Academic Institution
When transitioning a kidney transplant recipient from tacrolimus to cyclosporine, it is crucial to adjust the dose of mycophenolate mofetil due to significant pharmacokinetic interactions. Cyclosporine inhibits the enterohepatic recirculation of mycophenolic acid (MPA), the active metabolite of MMF,...
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