What is your approach to elevated urine uric acid levels in a recurrent calcium based stone former?
Answer from: at Academic Institution
There was good evidence from controlled trials supporting the use of allopurinol in hyperuricosuric calcium stone formers. That said, the trials are now pretty old and I would tend to treat other risks first (unless there was another reason to lower the uric acid like gout). In general, a lower anim...
Dr. @Lieske speaks for me also. The trial that showed the benefit of using allopurinol in calcium oxalate stone disease used the usual endpoint: A decrease in stone passages. The idea that allopurinol is a "super glue" for kidney stones makes no physiologic sense. In fact, how it would Physiological...