What is your approach to elevated urine uric acid levels in a recurrent calcium based stone former?

There was good evidence from controlled trials supporting the use of allopurinol in hyperuricosuric calcium stone formers. That said, the trials are now pretty old and I would tend to treat other risks first (unless there was another reason to lower the uric acid like gout). In general, a lower anim...

Dr. @Dr. First Last speaks for me also. The trial that showed the benefit of using allopurinol in calcium oxalate stone disease used the usual endpoint: A decrease in stone passages. The idea that allopurinol is a "super glue" for kidney stones makes no physiologic sense. In fact, how it would Physi...