What is your approach to maintenance of sotalol in terms of drug monitoring and duration of therapy for outpatients who remain in normal sinus rhythm?  

I have a healthy respect for the proarrhythmic potential of sotalol. I routinely load and increase the dose in the hospital setting. Not too dissimilar to dofetilide. I avoid as much as possible other drugs that prolong the QT interval and I use caution with other drugs that slow the HR. I monitor E...

I pretty much agree with Dr. Courson. I almost always load/change the dosage of sotalol in the hospital. I will monitor the patients closely thereafter, with frequent assessment of renal function and ECG.