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Topics:
Radiation Oncology • Gynecologic Cancers
What is your management strategy for unresectable endometrial cancer due to gross cervical involvement with parametrial extension?
If the patient is responding to external beam and likely to be converted to resectable, what brachytherapy dose/fractionation do you prescribe and what volume do you cover?
Answer from: Radiation Oncologist at Community Practice
Our approach is PETCT and MRI for staging. Neoadjuvant chemo RT with external beam and brachy to EQ2 dose of 65-70 Gy folllowed by extrafascial hysterectomy and then adjuvant chemotherapybelow is link to our published datahttps://www.ncbi.nlm.nih.gov/pubmed/25218303
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Answer from: Radiation Oncologist at Academic Institution
I am not totally sure of the value of chemotherapy with the pre-operative RT, although I can understand that recommendation. If patients are going to have a major operation following pre-op RT, there is also a downside to it. Just like in cervical cancer with parametrial extension, it could well be ...