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What is your methotrexate initiation strategy in DMARD-naive RA patients?
Specifically: starting dose, rapidity of up-titration, frequency of lab monitoring, frequency of office visits, and timing of assessment for treatment response.
Answer from: at Academic Institution
Starting with 10-15 mg/week, monthly labs x 3 months, then every 3 months thereafter for CBC +diff, AST, Creatinine; assessment at 3 months with up-titration.
If started with 10 mg/week, up-titrate to 15 mg in 2-4 weeks if well tolerated.
Comments
at Parkview Physicians Group Rheumatology
Any need to do ALT also?
Any need to do ALT also?
at Mayo Clinic
At baseline AST and ALT; at subsequent checks, our...
At baseline AST and ALT; at subsequent checks, our...
at UTMB Health
I agree with Dr. @Elena Myasoedova. In addit...
I agree with Dr. @Elena Myasoedova. In addit...
at Mayo Clinic
Yes, agree: we screen for Hep B and C, QuantiFERON...
Yes, agree: we screen for Hep B and C, QuantiFERON...
I usually stop at 20 mg weekly, especially when us...