What is your neoadjuvant chemotherapy of choice in patients with ER+ breast CA who are receiving neoadjuvant therapy with goal to convert to BCS from mastectomy?
Would your decision for anthracycline change if the patient were elderly?
Answer from: Medical Oncologist at Academic Institution
I have tried to use Dose dense doxorubicin and cyclophosphamide followed by dose dense paclitaxel (AC-T) in most situations in the neoadjuvant setting since lymph node status is not known definitively prior to surgery. There is adjuvant data from the ABC trial for non inferiority of docetaxel and cy...