What is your preferred management for a patient who was treated with definitive chemoradiation for locally advanced cervical cancer who now has a biopsy-proven isolated brain metastasis 5 years later?   

This is a rare occurrence, and there is no prospective clinical trial data that I am aware of to guide recommendations. In the literature, most seem to advocate for multimodal therapy with resection or stereotactic radiosurgery followed by whole brain radiotherapy for solitary brain lesions without ...