What is your preferred sequencing of adjuvant chemotherapy and PMRT for node + breast cancer?

I addressed this issue for patients treated with breast-conserving surgery in May 2023; please see that answer for more details. To summarize, the toxicities from chemotherapy may be greater and its effectiveness reduced (at least for high-risk patients) when given after RT instead of before (Recht ...

Chemotherapy followed by PMRT. In the modern era, no strong argument but may be for positive margin or driven by the patient's desire (social or personal commitments).