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Topics:
Radiation Oncology • Neuro-Oncology
What is your preferred treatment choice for GBM that crosses the corpus callosum?
Should an agressive attempt at resection be made? Do factors like age, KPS, MGMT status play a role in how aggressive of a push for surgery you make?
Answer from: Radiation Oncologist at Academic Institution
We never push for aggressive surgery in this case. The surgeons will not resect disease from the corpus callosum (due to resulting neurological issues), so further attempt of surgery would delay therapy in a group of patients that tend to do poorly, despite favorable prognostic factors.
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