What is your preferred treatment dose and schedule for capecitabine for patients with metastatic breast cancer?  

In the literature, the 1000 mg/m2 BID for 14 days on/7 days off has similar efficacy (J Clin Oncol. 2005) and lower toxicity (Breast Cancer Res Treat. 2016) than 1250 mg/m2.  Because of variations in our group, one of our clinical pharmacists reviewed all of our patients based on different dosi...