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Hematologic Malignancies • Medical Oncology • Bone Marrow Transplant • Internal Medicine • Hematology
What is your threshold for transfusing platelets in an asymptomatic patient after autologous stem cell transplant?
My practice had always been to transfuse for plts < 10, but the recent ASCO guideline change suggests that in the post-autoSCT setting it is reasonable to only transfuse platelets when the pt is actively bleeding, regardless of platelet count.
Answer from: Medical Oncologist at Academic Institution
My thresold for transfusing platelets in an asymptomatic patient after autologous stem cell transplant is the same as with other patients - transfuse for plts<10 unless febrile or if any bleeding complications, at which time the threshold would be higher.
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Answer from: Medical Oncologist at Academic Institution
We believe that the threshold of less than 10 is appropriate for patients with low risk of serious bleeding for patients who received chest XRT as part of their conditioning regimen or those with CNS lesions we increase our threshold to 50 since risk of devastating bleeding complications have been s...
Answer from: Medical Oncologist at Academic Institution
I continue to use <10,000 or bleeding as my trigger for autologous transplant patients.