What is your TKI preference in patients with chronic phase CML on hemodialysis?
Answer from: Medical Oncologist at Academic Institution
When choosing a TKI for patients on HD, it's important to know that TKIs are unlikely to be dialyzed. TKIs are mainly eliminated via the feces with small amounts eliminated by the kidneys. TKIs with the least amount of renal elimination theoretically should be preferred. Nilotinib and bosutinib have...