What regimen would you recommend for a younger, fit, transplant eligible patient with relapsed IDH1 positive AML?   

If there was only one answer! The decision revolves around co-occurring cyto and molecular genetic abnormalities (in addition to IDH1) and the duration of remission in first CR. In general, IDH mutant AML - without other high-risk genetic lesions - is very responsive to all of our treatments whether...