What systemic therapy, if any, would you offer a patient after WBRT for an isolated CNS relapse of initially limited stage SCLC that received chemoRT without PCI?

Would the timing of the relapse (eg within 6 months) impact your decision making?

Answer from: Medical Oncologist at Academic Institution

Since the patient has not progressed outside the CNS, I would hold off on any further therapy till there is evidence of extracranial progression.