What treatment would you consider for metastatic urachal carcinoma following progression on FOLFOX and FOLFIRI?
Molecular profiling revealed no targetable alterations, however tumor mutational burden was >10 mut/Mb.
Answer from: Medical Oncologist at Academic Institution
Metastatic urachal adenocarcinoma is a challenging disease to treat with significant unmet needs. Initial therapy replicates therapy for metastatic colorectal adenocarcinoma and may include FOLFOX, FOLFIRI or FOLFOXIRI potentially combined with bevacizumab. Salvage therapy may include 1) trials (gui...
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Medical Oncologist at University of Washington School of Medicine Great comments by the expert @Guru Sonpavde; regar...
Great comments by the expert @Guru Sonpavde; regar...