What volumes would you treat and what dose constraints do you use for breast and lymphatic re-irradiation?
In a patient who had BCS and adjuvant radiation to the breast and regional nodes, now several years later with extensive axillary recurrence s/p axillary dissection with concern for residual disease.
Answer from: Radiation Oncologist at Community Practice
H&N cancer brachial plexus re-irradiation data, “Among patients with a Dmax greater than vs less than 106 Gy, the 1-year cumulative incidence of brachial plexopathy (BPP) was 42% vs 4% P = 0.005. V80 > 1cc (1-yr cumulative incidence BPP 34% vs 4% P = 0.0...
Answer from: Radiation Oncologist at Community Practice
I have done in a few situations for palliation and favored 1.2 BID to mid-30s limited to the area of residual disease warning patients of the potential risk of plexopathy.