When can you get a false negative result from RT-QuIC testing?  

The current sensitivity of CSF RT-QuIC is thought to be 92%, and the specificity is 100%. The interpretation of the RT-QuIC is affected by the presence of raised CSF red and white cells and elevated total protein concentrations. In VPSPr (Variably Protease-Sensitive Prionopathy), CSF RT-QuIC is posi...