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When do you start anticoagulation for secondary prevention in patients with HFrEF and history of embolic strokes?
For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary prevention considering all current studies (ie, WARCEFF trial)?
Answer from: at Academic Institution
Current guidelines consider anticoagulation in patients with reduced EF as class III (no benefit and possibility of harm), which has not changed significantly since WARCEF was published. The most recent randomized large trial, COMMANDER HF, looked at primary stroke prevention (among other thrombotic...
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