Would you consider offering salvage radiation to a patient with castrate resistant prostate cancer who has never had local therapy and has no evidence of lymph node or distant metastasis?

It's hard to give a great answer without knowing more information, such as the PSA, Gleason score and T-stage at presentation, why he was treated with androgen deprivation alone up front, what AD he was treated with, how long he was under treatment before he became castrate resistant, and what is th...

I have treated patients in this situation several times over the years and none of them were ever controled over the long haul. They all appear to fail. Thus, it appears that whatever the changes are that make the prostate cancer hormone insensitive also make it very difficult to cure with RT. This ...