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Would you consider over-the-counter dextromethorphan (low dose, slow titration) as augmentation in MDD?

Considering a growing interest in the use of dextromethorphan for depression (Majeed et al., PMID 33682569).

Answer from: at Community Practice

I have used prescribed generic bupropion + dextromethorphan as a means of mimicking Auvelity without the hefty price tag. The prescribing info for Auvelity is to start with one tab (dextromethorphan 45 mg/bupropion 105 mg) and increase to BID (morning and 8 hours after first dose) after 3 days. What...

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Did they have good weight control? I have ask...

Please select the option that best describes you:

Would you consider over-the-counter dextromethorphan (low dose, slow titration) as augmentation in MDD?

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