Would you consider SBRT for multiple bilateral lung primaries and/or a lung primary with metastases to multiple lobes?  

This is a difficult situation. There is not a ton of information on SBRT for synchronous lung nodules. Ironically I'm on one of the articles (Owen et al. Radiation Oncology, 2015). We treated 60+ patients with multiple nodules but many of them were metachronus, which is a bit different situation. Si...

I agree with Dr. @Kenneth Olivier's thoughtful response from 5 years ago. Our group has some institutional data in a manuscript currently under review on 60 patients treated to synchronous lung primaries with SBRT simultaneously. Based on this, I believe that treating 2 or occasionally even 3 simult...

I generally agree with the provided discussions. There is very little data. In my experience, I will treat a number up to the dose constraints (usually lung) that I would use for a stage III NSCLC. Practically, this depends on the size of the lesions and their proximity to each other. Of course, I r...