Would you dose-escalate the radiation prescription for patients with radioresistance SNP's in ERCC1 or ERCC2?
For example, in locally advanced NSCLC would you dose-escalate beyond 60 Gy?
Answer from: Radiation Oncologist at Community Practice
The current practice does not require testing of ERCC1 or ERCC2 SNPs, so such data is not available for us in the clinic. I am not sure if I can order such a test in the practice and if the Health Insurance would cover such test.
Using this biomarker signature, we are going to open a trial to...