Would you offer APBI in patients with a high Oncotype who are otherwise considered “suitable” per ASTRO guidelines?

What if the patient is refusing chemotherapy?

Answer from: Radiation Oncologist at Community Practice

I would be reluctant based on limited data showing high oncotype predicting for increased risk of local relapse even after RT. I would favor treating with whole breast plus a boost.

Comments

Radiation Oncologist at Maryland Oncology Hematology
Would you do the same for intermediate risk Oncoty...

Radiation Oncologist at Varian Medical Systems/Allegheny health network
APBI.

Answer from: Radiation Oncologist at Academic Institution

I have offered patients with high risk oncotype APBI as I have not seen strong data that high oncotype predicts for LRR and that WBI mitigates that risk as compared to APBI. That being said WBI with boost is completely appropriate as well.

Comments

Radiation Oncologist at Lake Huron Medical Center
Interesting - in the triple negative population, y...

Radiation Oncologist at Cleveland Clinic
Agreed, there is definitely grey. Usually, ER- don...

Radiation Oncologist at Lake Huron Medical Center
I think a lot of the grey area is about high risk ...

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Would you offer APBI in patients with a high Oncotype who are otherwise considered “suitable” per ASTRO guidelines?

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