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Topics:
Breast Cancer • Radiation Oncology
Would you offer partial breast irradiation to women who have HER2+ disease?
If so, do you give RT before or after adjuvant chemotherapy?
Answer from: Radiation Oncologist at Academic Institution
I agree with others that in the era of effective anti-HER2 systemic agents, the likelihood of in-breast recurrence can be very low for HER2 positive breast cancer patients undergoing breast conserving therapy. On the other hand, there is little to no prospective data regarding the efficacy of APBI. ...
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Answer from: Radiation Oncologist at Community Practice
With respect to HER2+ disease, I do offer partial breast irradiation if other features are appropriate. In early stage patients receiving HER2 targeted therapy, data from the APT trial showed low rates of locoregional recurrence supporting partial breast irradiation for this cohort of patients. In t...
Comments
Radiation Oncologist at Varian Medical Systems/Allegheny health network
Agree, as in the anti HER2 nu therapy era, the ris...
Agree, as in the anti HER2 nu therapy era, the ris...
Radiation Oncologist at University of Michigan Medical School
Would the recommendation (whole breast/APBI) be di...
Would the recommendation (whole breast/APBI) be di...
Radiation Oncologist at Allegheny Health Network, Pittsburgh
If ER/PR is negative and HER2 is positive and not ...
If ER/PR is negative and HER2 is positive and not ...