Would you offer SBRT/hypofractionation for stage I NSCLC with positive margins after resection?

I agree that it feels a bit disingenuous, in an era where we can provide precision delivery to areas of the lung with high control rates and low toxicitity, to offer standard PORT over 5-6 weeks.

However, I think the first question is not how to delivery RT, but whether to deliver it?

The most relevan...

I agree that this is a tough situation. Although the ACOSOG trial showed no difference in LR statistically, it did decrease the crude failure rate. That being said, our surgeons feel uncomfortable observing this group of patients.

From a practical standpoint, many of these patients have medical indi...

As one of the co-authors of ACOSOG Z4032, I agree that focally-directed therapy (it doesn't get any more focal than brachytherapy) did not pan out to be beneficial despite our institutional experience at the time which formed the basis for the ACOSOG trial. I don't think the state of the literature ...