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Topics:
Neuro-Oncology
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Pediatric Hematology/Oncology
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Neurology
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Child Neurology
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Pediatric Oncology
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Neurodevelopmental Disabilities
Would you recommend a specific workup or change in management for patients with severe, persistent deficits from methotrexate leukoencephalopathy?
Related Questions
What workup do you consider for a developmentally typical child with multiple large café au lait macules but no other signs of neurofibromatosis?
At what point should surgical intervention be considered for vestibular schwannomas or other tumors in pediatric NF2 patients?
What is the expected timeframe for the development of radiation myelitis and therapies that have helped with neurologic symptoms?
In pediatric patients with low-grade gliomas showing prolonged response or stable disease on tovorafenib, how would you adjust the duration of therapy?
How do different inflammatory markers like CRP and ferritin contribute differently, if at all, to the monitoring of CART neurotoxicity?
How do you approach anti-seizure medication management when it was started by another team for a seizure-naive patient before/after craniotomy for a tumor?
How has the recent FDA approval of tovorafenib impacted your treatment decisions for pediatric patients with relapsed/refractory low-grade glioma?
Based on the FIREFLY-1 data, would you consider using tovorafenib monotherapy front-line in pediatric patients who have low grade gliomas that are only amenable to subtotal resection or are unresectable?
What approach do you use when treating adult diffuse gliomas with H3-G34 mutations, now classified into their own category under the 2021 glioma guidelines?
Would you offer adjuvant radiation therapy in a young adult with NF1 who has a craniopharyngioma s/p STR?
