Would you treat a patient with ESRD on hemodialysis and penile cancer with neoadjuvant ifosfamide?

I do not have a particular expertise in penile cancer. My sense is that neoadjuvant therapy in general is not of proven value in penile cancer and, in someone like this with ESRD, likely to be more toxic than beneficial. The immunotherapy question is interesting, but there are no data to support suc...