Would you use OncoType Dx to guide adjuvant therapy recommendations in the context of locally recurrent, node-negative, ER+ breast cancer previously treated with endocrine therapy alone?

No oncotype was sent on the original breast cancer.

Answer from: Medical Oncologist at Community Practice

Assuming that 1.) the recurrence is in ipsilateral breast tissue post-radiation therapy, 2.) the patient is on adjuvant hormone therapy, and 3.) the pathologist concurs that this is not a new primary, we could approach this problem on multiple fronts.1.) Does the tumor harbor an ESR1 mutation? Altho...

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Medical Oncologist at NYU Winthrop Hospital
Great review.

Medical Oncologist at Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
Would you use Oncotype Dx to guide adjuvant therap...

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Would you use OncoType Dx to guide adjuvant therapy recommendations in the context of locally recurrent, node-negative, ER+ breast cancer previously treated with endocrine therapy alone?

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