Would you use sutimlimab for cold agglutinin disease/syndrome in patients with a concurrent hematologic malignancy?  

The CARDINAL trial excluded patients with active malignancy, and thus in general I would not use sutimlimab in patients with CAD in context of a concurrent hematologic malignancy. Additionally, one would hope that treating the hematologic malignancy would address CAD mediated hemolysis, without requ...