Would you wait to treat a ground glass opacity lesion (minimally invasive adenocarcinoma or adenocarcnioma in situ) with SBRT until there is more of a solid component?

In my experience, it seems like the post-SBRT area of fibrosis is more than I would have otherwise expected with GGOs. I have usually advised waiting until there is more of a solid component.

Answer from: Radiation Oncologist at Academic Institution

In general, it is understood that the appropriate indication for utilizing lung SBRT is in the setting of a diagnosis of invasive cancer, i.e., early stage lung cancer or an oligometastatic lesion. With regard to ground glass opacities (GGOs) it is understood that the differential for these entities...

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Radiation Oncologist at University of Colorado School of Medicine
Interestingly, this patient with the 6 cm pure GGO...

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Would you wait to treat a ground glass opacity lesion (minimally invasive adenocarcinoma or adenocarcnioma in situ) with SBRT until there is more of a solid component?

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