Are cavitary lung lesions a contraindication to TKIs/VEGF inhibitor use in renal cell carcinoma?   

There is a potential risk of neutropenia or leukopenia with TKI use in RCC patients. Nevertheless, none of the clinical trial data showed increased infection with their use (Reinwald et al., PMID 27127405). However, a cavitary lung lesion can be due to serious infection caused by aggressive or oppor...