Please select the option that best describes you:
How do you manage hypoxia induced by belzutifan?
Would you reduce dose prior to adding supplemental oxygen?
Answer from: Medical Oncologist at Community Practice
Hypoxia is an on-target adverse effect (AE) of belzutifan. All-grade hypoxia was reported in 14.5% of patients (10.5 %, grade 3 and above) in the LITESPARK-005 trial (Choueiri et al., PMID 39167807). Discontinuation of belzutifan due to hypoxia was <1%. Of note, patients with hypoxia (<9...
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