Are docetaxel and paclitaxel interchangeable for stage II-III HER2+ breast cancer patients receiving neoadjuvant chemotherapy with AC-THP?

Are there any studies that compare them?

Answer from: Medical Oncologist at Academic Institution

I believe docetaxel and paclitaxel are interchangeable in AC-THP for neoadjuvant chemotherapy for HER2 positive early-stage breast cancer. Decent phase II data from MSKCC confirm that the paclitaxel combination is well tolerated with PFS similar to CLEOPATRA.(Dang et al., PMID 25547504).The larger q...

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Medical Oncologist at Warren Alpert Medical School of Brown University
I agree with Dr. @Adam Brufsky that docetaxel...

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Are docetaxel and paclitaxel interchangeable for stage II-III HER2+ breast cancer patients receiving neoadjuvant chemotherapy with AC-THP?

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