How would you treat a patient with HER2 positive CNS only progression on fam-trastuzumab which had previously progressed on tucatinib/capecitabine/trastuzumab, and has failed both SRS and WBRT?
Answer from: Medical Oncologist at Academic Institution
I would present or refer her case to a multidisciplinary tumor board to 1) review her MRI to confirm there is progression vs. therapy changes, 2) see if she is a candidate for resection or irradiation of the progressing lesion (possibly using bevacizumab to reduce risk of radiation necrosis), and 3)...
Comments
Medical Oncologist at Houston Cancer Treatment and Immunotherapy Center Agree!
Medical Oncologist at NYU Winthrop Hospital Tough case, poor outcome
Medical Oncologist at University of Utah Any thoughts on special MRI sequences to delineate...
Radiation Oncologist at University of Arizona A multiparametric MRI using perfusion sequences ca...
Agree!
Tough case, poor outcome
Any thoughts on special MRI sequences to delineate...
A multiparametric MRI using perfusion sequences ca...