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Radiation Oncology • Genitourinary Cancers
Are there any situations in which you would offer postoperative RT for node positive prostate cancer?
Answer from: Radiation Oncologist at Academic Institution
The textbook answer, based on Messing NEJM, is ADT for node+ patients post-prostatectomy, but this is certainly a moving target.As node+ patients were excluded from all adjuvant (EORTC, German, and SWOG) and salvage (RAVES, RTOG 0534) randomized trials, there is currently no level I evidence for XRT...
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Answer from: Radiation Oncologist at Community Practice
In large Italian study two subset which benefited most from adjuvant RT for node positive prostate cancer were patients with positive lymph node (PLN) count ≤ 2, Gleason score 7 to 10, pT3b/pT4 stage, or positive surgical margins (HR, 0.30; P = .002); and (2) patients with PLN coun...