Can bicalutamide be used instead of LHRH agonist in intermediate to high risk prostate patients receiving EBRT who want to preserve erectile function?  

The short answer is yes, BUT with some serious reservations: 1. This is not considered standard of care in this patient population, so patients should be made aware of that fact and that conversation should be documented in the medical record; 2. There are data to indicate that bicalutamide plus EBR...

The question is "can" bicalutamide be used? Yes it "can". The real question is "should" it be used...the answer is usually no.There is only 1 modern trial that looked at this question for intermediate risk men. It was the PMH 9907 trial. Patients all received dose escalated EBRT. Median followu...

Some of my patients will refuse therapy if it includes ADT. The sexual side effects of ADT are only one factor that make the side effects from ADT unacceptable to some men. They read on the internet about cognitive issues, hot flashes and weight gain. Also the reduction in muscle mass can be dram...