For recurrent prostate cancer after prostatectomy with soft tissue mass in the prostate fossa, is hypofractionation an option or is standard fractionation recommended?  

There is no standard, accepted modification of a treatment plan for the detection of gross residual/recurrent disease in the operative bed; however, a few common approaches have been reported. These options, as they pertain to hypofractionated treatment regimens are discussed below.  Treatment...

SIB 72/2 Gy to nodule and 64.8/1.8 Gy to entire prostate bed in 36 fractions with at least 6 months or up to 2 years ADT depending on risk factors and comorbidities.

I will have to read Dr. @Patel's essay above, and I may change what I do, but for 10 years I’ve been doing 70/70.2 to the fossa standard fraction with a sequential boost to the nodule taking to 75-76. Probably done it this way more than 100 times. I used to go up to 79.2 many years ago becaus...